Clubs
- American Sign Language Club
- Anime Club
- Biology Olympiad
- Creative Writing Club
- DEBS
- DECA
- Ethics Bowl
- Fellowship of Christian Athletes
- French Honor Society
- Girls Bible Study
- GSA
- HOSA
- International Thespian Society (Drama Club)
- Key Club
- Maryville Connected
- MHS Investment Club
- Model United Nations
- Mu Alpha Theta
- National Art Honors Society
- National Honor Society
- Prom Committee
- Rebel Readers Book Club
- Scholars Bowl Team
- Science Bowl
- Science Olympiad Team
- Spanish Honor Society
- Student Council