Clubs
- American Sign Language
- American Sign Language Honor Society
- Anime
- Biology Olympiad
- Blount County Student Wellness Coalition
- Creative Writing
- DECA
- Dungeons & Dragons
- Ethics Bowl
- Fellowship of Christian Athletes (FCA)
- French Honor Society
- Gay-Straight Alliance (GSA)
- Girls Bible Study
- HOSA
- International Thespian Society (Drama Club)
- Key Club
- Maryville Archery
- Maryville Connected
- Maryville Investment Club
- Maryville Progressives
- Model United Nations
- Mu Alpha Theta
- National Art Honors Society
- National Honor Society
- Outdoor Club
- Prom Committee
- Rebel Readers
- Robotics
- Scholars Bowl Team
- Science Club
- Science Olympiad Team
- Spanish Honor Society
- Student Council
- Tri-M Music Honor Society
- Unified Special Olympics